Conditions x NMN - 40-Condition Evidence Review

40 health conditions reviewed against NMN evidence - Yoshino 2021, Igarashi 2022, animal data, and where the gaps are. ICD-10 coded, evidence-tiered, contraindications listed. Malaysian medical context throughout.

6 deep-dive long-form reviews (2,200-2,800 words each) cover the highest-evidence conditions: prediabetes, perimenopause, sarcopenia, type-2 diabetes, metabolic syndrome, fatty liver (NAFLD). The remaining 34 conditions render as evidence-tiered short-form reviews.

cardiovascular

Hypertension mechanistic-only
Atherosclerosis mouse-only
Heart Failure mouse-only
Ischemic Heart Disease mouse-only

dermatological

Skin Photoaging mechanistic-only
Androgenic Hair Thinning no-evidence

hepatic

Non-Alcoholic Fatty Liver Disease mouse-only
Non-Alcoholic Steatohepatitis mouse-only

longevity

Biological Aging preliminary-human
Age-Related Fatigue preliminary-human
Immunosenescence mouse-only
Telomere Shortening no-evidence
Chronic Fatigue Syndrome (ME/CFS) mechanistic-only
Post-COVID Fatigue preliminary-human

metabolic

Type 2 Diabetes preliminary-human
Prediabetes preliminary-human
Metabolic Syndrome mechanistic-only
Obesity no-evidence
Insulin Resistance preliminary-human
Hyperlipidemia no-evidence

musculoskeletal

Sarcopenia preliminary-human
Osteoporosis mouse-only
Knee Osteoarthritis no-evidence
Frailty preliminary-human
Mitochondrial Myopathy preliminary-human

neurological

Alzheimer's Disease mouse-only
Parkinson's Disease mouse-only
Mild Cognitive Impairment mechanistic-only
Age-Related Cognitive Decline mechanistic-only
Stroke Recovery mouse-only
Jet Lag no-evidence
Age-Related Hearing Loss (Presbycusis) mouse-only
Glaucoma mouse-only
Dry Eye Disease no-evidence
Age-Related Macular Degeneration mechanistic-only

renal

Chronic Kidney Disease mouse-only

reproductive

Perimenopause no-evidence
Menopause preliminary-human
Female Fertility Decline mouse-only
Male Fertility Decline and Andropause no-evidence