Should I stop NMN before surgery?

Yes, conservatively stop 7-14 days before scheduled surgery and resume after the surgical team clears you. The reasoning is similar to standard pre-operative supplement holds. Surgery involves controlled tissue trauma, anaesthesia metabolism, blood loss, and a measurable inflammatory response. Anaesthesiologists prefer patients on the cleanest possible drug profile so that surgical complications can be attributed accurately. NMN itself has no clear bleeding or coagulation effect - it does not thin blood the way fish oil, ginkgo, or vitamin E might. There are no documented anaesthetic interactions. The 7-14 day hold is conventional caution, not a specific NMN risk. For Malaysian patients planning elective procedures (cataract surgery, gallbladder removal, joint replacement, cosmetic procedures): tell your surgeon and anaesthesiologist about NMN at the pre-op clinic 2-3 weeks before the date. They will likely instruct you to stop alongside other supplements (multivitamins, fish oil, herbal preparations). Resume NMN once you are eating normally, walking, and your post-op review confirms uneventful recovery - typically 2-4 weeks post-op for major procedures, sooner for minor day-cases. Emergency surgery cases do not have time for this protocol - disclose your supplement use during the admission interview but do not delay essential treatment. Major Malaysian private hospitals (Pantai, Sunway Medical, Gleneagles, Subang Jaya Medical Centre) routinely ask about supplements during pre-op assessment; be honest and complete in your disclosure.

Why this matters for Malaysian buyers

NMN buying decisions in Malaysia involve a stack of considerations that don't always map to advice from US- or EU-focused sources: NPRA notification status, JAKIM halal certification (or its absence), tropical-climate storage realities, mall pharmacy versus Shopee Malaysia tradeoffs, and how local medical practitioners typically respond to questions about supplements outside their training. We answer questions like "Should I stop NMN before surgery?" through the lens of Malaysian buyer realities - not generic global guidance.

Verify the source

This individual Q&A is a supporting note, not an indexable authority article. Health-relevant claims should be refreshed against the linked primary or official sources before they are used for buying or medical discussions.

• Oral Administration of Nicotinamide Mononucleotide Is Safe and Efficiently Increases Blood Nicotinamide Adenine Dinucleotide Levels in Healthy Subjects (2022)
• Safety evaluation of β-nicotinamide mononucleotide oral administration in healthy adult men and women (2022)
• The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial (2023)
• National Pharmaceutical Regulatory Agency (NPRA) Malaysia - Quest3+ MAL Number Registry (2026)
• Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men (2022)

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