Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study
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Plain-language summary
Published 2021 in Journal of the International Society of Sports Nutrition, this work by Liao B and collaborators tackles a specific question within benefits-focused NMN/NAD+ research.
Key findings reported by the authors
- 6-week NMN dose-response (300, 600, 1200 mg/day) in amateur runners
- VO2 and ventilatory thresholds improved dose-dependently
- Time-to-exhaustion improved at higher doses
What this means for Malaysian buyers
For readers in Malaysia weighing whether to start or continue NMN supplementation, this paper sits at the moderate end of the evidence spectrum. Moderate-tier evidence usually means a small human trial or a well-designed mouse study; helpful for hypothesis-building but not for hard recommendations. Findings here are most directly relevant to benefits decisions, with secondary relevance to dosage. Our editorial methodology weights human placebo-controlled trials above mouse mechanistic work above review articles.
Where we cite this paper
- NMN Dosage in Malaysia: What the Human Trials Actually Used
- Is NMN Safe? Evidence-Based Review for Malaysians
- NMN Side Effects Explained: What Trials Actually Reported
- NMN Benefits: What the Human Evidence Actually Shows
- NMN for Energy: What the Mitochondrial Evidence Actually Shows
- Is NMN Worth It? The Real RM Cost-Per-Year for Malaysians
- NMN vs NR vs NAD+ IV: Complete Comparison for Malaysians
- Where to Buy NMN in Malaysia: KL, Penang, JB Local Guide
- NMN Influencer Claims Fact-Checked: Sinclair, Huberman, Attia
- Your First 30 Days on NMN: A Realistic Week-by-Week Roadmap
- NMN Quick Start: Your First 7 Days, Malaysia Edition