Dr. Samuel Trammell

Postdoctoral Researcher (formerly Brenner Lab) | University of Iowa

About

Lead author of Trammell 2016 - the foundational NR pharmacokinetics paper. Demonstrated NR's bioavailability and dose-response NAD+ elevation in humans at 100, 300, and 1000mg. The trial set the standard for human NR dosing across the field.

Key contributions

• Trammell 2016 NR PK paper
• Dose-response NAD+ in humans
• NR bioavailability framework

Publications in our knowledge base (2)

Every paper below is cited at least once across NMN Malaysia articles. Click any title to read the source on PubMed/DOI and see the cluster of articles that depend on its findings.

• Safety and metabolism of long-term administration of NIAGEN (NR) in healthy overweight adults
  2019 | Scientific Reports | evidence: strong
  Conze D, Brenner C, Kruger CL
  • NR 1g/day for 8 weeks well tolerated
  • Statistically significant NAD+ elevation
  • No clinically meaningful adverse events
• Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
  2016 | Nature Communications | evidence: strong
  Trammell SAJ, Schmidt MS, Weidemann BJ, Redpath P, Jaksch F, et al.
  • Demonstrated oral NR bioavailability in humans
  • Frequent comparator paper for NMN bioavailability claims
  • Brenner's lab - opposing camp to Imai's NMN focus

Why their work matters for Malaysian buyers

Dr. Samuel Trammell's research forms part of the evidence base we use to evaluate NMN and NR products available in Malaysia. When we make claims about dose ranges, safety, mechanism, or efficacy on this site, those claims trace back through papers like the ones above. The Malaysian regulatory framework (NPRA notification, JAKIM halal certification) does not perform efficacy review on supplements - buyers must do their own evidence weighting. Researcher profiles help you verify that the underlying science is robust, not just marketing.

How we cite this work

Every NMN Malaysia article that depends on findings from Dr. Samuel Trammell's lab carries an inline citation linking to a structured PubMed entry. You can verify any claim by clicking the citation and reading the source. This cited-research model is the bedrock of our editorial policy - see the 4-step review process for how we handle every health claim.

Related researchers

Browse other profiles: David Sinclair | Shinichiro Imai | Jun Yoshino | Charles Brenner | all profiles.

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